Storm damage closes N.C. factory that makes vital hospital supplies

As the remnants of Hurricane Helene moved inland, the storm flooded a factory that makes intravenous fluids used in hospitals around the country.

The Baxter International factory in Marion, N.C., about 35 miles outside of Asheville, was evacuated right before the worst of the storm passed, according to social media posts from employees. It’s now shut down and covered in mud — like a lot of western North Carolina. Bridges leading to the facility were also badly damaged.

The facility is one of the largest suppliers of IV fluids in the country, the Food and Drug Administration says. Baxter says it will spare no expense to get the factory back online, but the company doesn’t “have a timeline for when operations will be back up and running.”

The plant’s closure, which could last weeks or even months based on similar situations in the past, could strain the supply of vital health care products.

“The kinds of things that are made at this factory are drugs that we’re using every day. And in the case of sodium chloride in particular, potentially for every patient ,” says Dr. Alison Haddock, president of the American College of Emergency Physicians.

IV fluids, like sterile water, saline and fluids with carbohydrates, are used all the time in hospitals, surgery centers, nursing homes and dialysis centers. Some drugs have to be given with IV fluid. And sometimes emergency room patients can’t have anything by mouth while they’re being evaluated in case they need surgery, so they’ll get an IV to stay hydrated.

“It is the rare patient in the emergency department that doesn’t end up with some IV fluids in the course of their evaluation and treatment, sort of regardless of their chief complaint,” Haddock says.

Baxter and the government get to work

Work has already begun to get the factory back up and running with about 500 people on site, the company says. “We expect this number to double in the week ahead.”

The FDA is also working with Baxter and other parts of the government to get a handle on the situation. The agency says it may look at temporarily allowing imported IV fluids to avoid shortages.

Baxter is limiting orders to prevent panic-buying that could make things worse and to make sure that the existing supply of IV solutions is distributed evenly.

“My hospital has been told we can expect 40% of what we normally order,” Chris Laman, vice president of strategy for Columbia Memorial Hospital in Astoria, Ore., told NPR in an email. “We are talking about having to limit elective surgeries.”

Baxter also sent a letter to hospitals suggesting they reevaluate their protocols for IV fluids to make sure they’re going to the people who really need them and not being wasted.

How hospitals are handing the situation

It’s difficult for hospitals to stockpile IV fluids, the way they can with pills or vials of medicine, because IV fluids are bulky. Each liter bag weighs more than 2 pounds.

“They are large,” says Michael Ganio of the American Society of Health System Pharmacists. “And so hospitals, if they’re managing inventory on site, there’s only so much they can keep on hand at a time. And it may be a week to 10 days’ worth, depending on which specific solution we’re referring to.”

He says hospitals are already digging up old policies from when Hurricane Maria crippled a factory making similar products in 2017.

For better or worse, hospital pharmacists have been through this before.

“It’s good because we can manage it,” Ganio says. “We can deliver care to patients without the patient’s care being affected. It’s bad because it means that we’re just managing this. We’re accepting that it’s the status quo, and the patients aren’t learning about it.”

What to expect if you’re a patient

Most of the juggling will happen behind the scenes. Patients probably won’t even realize IV fluids are in short supply unless things get really dire. The hope is that the FDA and health care system can prevent that from happening.

But shortages could affect patients in the emergency room who come in with nausea and vomiting, for example.

Often, they would be given an IV bag for hydration. But with the limited supply of these bags, these patients might be given anti-nausea medication and asked to drink a Gatorade or Pedialyte instead. That conserves the IV bags for patients in the intensive care unit and those getting surgery.

It could become a difficult situation, but patients should know they’re in good hands, says Haddock, of the American College of Emergency Physicians. “We’re pros at this, and we’re going to figure out how to get you the care that you absolutely need, even if it’s not the easiest way.”

Transcript:

A MARTÍNEZ, HOST:

As Hurricane Helene swept through western North Carolina, it flooded a factory that produces IV fluids used by hospitals all across the country. That means hospitals could soon face shortages. Sydney Lupkin is NPR’s pharmaceuticals correspondent. Sydney, what happened at that factory?

SYDNEY LUPKIN, BYLINE: So that factory is in Marion, N.C., about 35 miles east of Asheville, and it was evacuated right before the worst of the storm passed. That’s according to social media posts from employees. It’s now shut down and is covered in mud, like a lot of the area. The facility is owned by Baxter International, and it’s the company’s biggest plant. It makes IV fluids – sterile water, saline fluids mixed with some carbohydrates.

MARTÍNEZ: Yeah. That’s those bags that hang on poles next to hospital beds. But, I mean, aren’t those bags everywhere?

LUPKIN: Yeah. They really are. They’re used all the time in hospitals and surgery centers, not to mention dialysis centers. Here’s Dr. Alison Haddock, president of the American College of Emergency Physicians.

ALISON HADDOCK: It is the rare patient in the emergency department that doesn’t end up with some IV fluids in the course of their evaluation and treatment, sort of regardless of their chief complaint.

LUPKIN: Some drugs have to be given with IV fluid. Sometimes, emergency room patients can’t have anything by mouth while they’re being evaluated, just in case they need surgery, so they’ll get an IV to stay hydrated.

MARTÍNEZ: All right. Now, with that factory shut down then, what does that mean for the supply of those IV fluids?

LUPKIN: So the Food and Drug Administration says this was one of the largest suppliers of IV fluids in the country, and it’s working with Baxter and other parts of the government to get a handle on the situation. Baxter is limiting orders to prevent panic buying that could make things worse and to make sure that the existing supply of IV solutions is distributed evenly. One hospital executive told me he was only allowed to order 40% of his usual IV supply. Baxter also sent a letter to hospitals suggesting they reevaluate their IV fluids protocols to make sure they’re going to the people who really need them and not being wasted. The FDA says it may look at temporarily allowing imported IV fluids to avoid shortages.

MARTÍNEZ: I don’t understand. I would figure hospitals would have stockpiles of this stuff.

LUPKIN: Yeah. You would, but not as much as you might think. Unlike pills or vials of medicine, bags of IV fluids are really bulky. Each liter bag weighs more than 2 pounds. Here’s Michael Ganio of the American Society of Health-System Pharmacists.

MICHAEL GANIO: They are large, and so hospitals, if they’re managing inventory on-site, there’s only so much they can keep on hand at a time, and it may be a week to 10 days’ worth, depending on which specific solution we’re referring to.

LUPKIN: He says hospitals are already digging up old policies from a few years ago when Hurricane Maria crippled a factory making similar products in 2017. You know, for better or worse, hospital pharmacists have been through this before.

MARTÍNEZ: Then, OK, patients at hospitals and also patients at dialysis centers, I mean, how might they be affected?

LUPKIN: An example I’ve heard a few times is that an ER patient might be given an anti-nausea medication and asked to try to drink Gatorade or Pedialyte to hydrate rather than getting an IV. That could save some of these products for patients in the ICU and patients who are getting surgery. Most of the juggling, however, will happen behind the scenes. Patients probably won’t even realize anything is different unless things get really dire. The hope is that the FDA and health care system can prevent that from happening.

MARTÍNEZ: All right. NPR’s pharmaceuticals correspondent Sydney Lupkin, thanks a lot.

LUPKIN: You bet.

(SOUNDBITE OF BDAZZLED’S “FANTASIZE”)

 

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