In 2024, COVID dropped from the list of top 10 causes of death in U.S.

Pien Huang | September 10, 2025

Activists gather during a vigil in Washington D.C. for nurses who died during the COVID-19 pandemic on January 13, 2022. In 2021, more than 460,000 people died of COVID in the U.S. but last year it was around 47,000.

COVID-19 is no longer one of the top 10 causes of death in the U.S.

Early data on deaths in 2024, published by the Centers for Disease Control and Prevention, show that COVID dropped from the list for the first time since the start of the pandemic. It became the third leading cause of death in the U.S. in 2020, and remained among the leading causes until now.

“COVID is still in the top 15 leading causes of death, so it hasn’t disappeared,” says Farida Ahmad, a health scientist at the CDC’s National Center for Health Statistics and lead author on the publication.

Since its peak in 2021, when more than 463,000 people died from COVID, it has been moving steadily down the list. Last year, it was a factor in around 47,000 U.S. deaths.

Overall, deaths last year were down 4% from the previous year, and it was the third consecutive year of that downward trend, Ahmad says. The declines extend across the board, to most age groups and to people of all races and ethnicities, and can be attributed to a number of factors, such as fewer deaths from COVID and from drug overdoses, she says.

The leading causes of death included suicide, diabetes, kidney disease, and unintentional injury. Heart disease and cancer — both chronic diseases — remained the top two leading causes of death, as they have been for more than a decade, and were responsible for more than 40% of U.S. deaths in 2024.

Death rates were higher for men than women, for older adults, and for Black Americans compared with other racial and ethnic groups.

“The fact that we’re seeing people living into older and older age and dying of chronic diseases is a sign that we’ve been successful at dealing with infectious diseases,” says Kathleen Ethier, a former CDC official at the National Center for Chronic Disease Prevention and Health Promotion, who left the agency in January and was not involved in this paper.

Tackling chronic diseases takes a different strategy, Ethier says: “These are things that develop over time, that are highly impacted by our behavior and environments and genetics.”

With heart disease, for instance, a person may have higher risks if they have a family history of the condition, if they live in stressful or polluted environments, if they mainly eat ultraprocessed foods, and if they have spotty access to health care. “What kinds of food can people afford? Do they have insurance and money to pay for services? Those are difficult, entrenched things for public health to impact,” Ethier says.

Earlier this week, Health Secretary Robert F. Kennedy Jr. released a report titled “Make Our Children Healthy Again,” which drew mixed reviews from public health advocates, who note that its goals clash with other recent moves by the Trump Administration, including cuts to food assistance, scientific research, Medicaid programs and changes that limit access to vaccines.

“What this administration is doing is going to make the top ten causes of death worse,” says Ethier. She notes that President Trump’s FY 2026 budget targets the CDC division that’s focused on preventing chronic diseases for elimination in. This includes the office that deals with smoking, a major risk factor for heart disease, stroke and some cancers.