EXPLAINER: What’s known about sudden liver disease in kids
By LINDSEY TANNER AP Medical Writer
A puzzling outbreak of sudden liver disease in nearly 200 children has health authorities in Europe and the U.S. racing to find answers.
The illnesses have no known connection, although a possible link with a virus that can cause colds is being investigated. At least one child died and several others have required liver transplants.
What’s known so far:
The Basics
Previously healthy children are suddenly developing hepatitis, or liver inflammation often caused by viruses. Jaundice, diarrhea and abdominal pain are among reported symptoms. Children aged 1 month to 16 years have been affected.
Most cases have occurred in Europe. The first U.K. cases were recorded in January. The Centers for Disease Control and Prevention said in a nationwide health alert last week that the first U.S. cases were identified in October in Alabama.
The Disease
Hepatitis is usually caused by one of several contagious hepatitis viruses that have not been found in the affected children. Sometimes the disease is mild and requires no specific treatment. But severe cases require hospitalization and can lead to liver failure.
The Cause
Authorities are uncertain what is causing the outbreak. Nine children in the Alabama cluster tested positive for adenovirus. Some types of the virus can cause colds but authorities are also looking at a version that can cause digestive problems. It is unknown whether that virus is a cause or is somehow contributing to the outbreak.
Locations
Cases have been reported in at least a dozen countries, including Denmark, England, France, Ireland, Israel, Italy, the Netherlands, Norway, Scotland, Spain, and the United Kingdom. In the United States, cases have also occurred in Illinois and North Carolina.
The CDC says all physicians should be on the lookout for symptoms and report any suspected case of what’s called hepatitis of unknown origin.
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.
Auburn tabs USF’s Alex Golesh as its next coach, replacing Hugh Freeze on the Plains
The 41-year-old Golesh, who was born in Russia and moved to the United State at age 7, is signing a six-year contract that averages more than $7 million annually to replace Hugh Freeze. Freeze was fired in early November after failing to fix Auburn’s offensive issues in three seasons on the Plains.
Alabama Power seeks to delay rate hike for new gas plant amid outcry
The state’s largest utility has proposed delaying the rate increase from its purchase of a $622 million natural gas plant until 2028.
Former U.S. Sen. Doug Jones announces run for Alabama governor
Jones announced his campaign Monday afternoon, hours after filing campaign paperwork with the Secretary of State's Office. His gubernatorial bid could set up a rematch with U.S. Sen. Tommy Tuberville, the Republican who defeated Jones in 2020 and is now running for governor.
Scorching Saturdays: The rising heat threat inside football stadiums
Excessive heat and more frequent medical incidents in Southern college football stadiums could be a warning sign for universities across the country.
The Gulf States Newsroom is hiring an Audio Editor
The Gulf States Newsroom is hiring an Audio Editor to join our award-winning team covering important regional stories across Mississippi, Alabama and Louisiana.
Judge orders new Alabama Senate map after ruling found racial gerrymandering
U.S. District Judge Anna Manasco, appointed by President Donald Trump during his first term, issued the ruling Monday putting a new court-selected map in place for the 2026 and 2030 elections.
