Pig Hearts Could Keep Babies Awaiting Transplants Alive
Scientists hope in the future, pig hearts can be a temporary solution for babies who need a transplant. UAB researchers recently presented a study about this at The Society of Thoracic Surgeons’ annual meeting. The goal is to prevent pig hearts from being rejected. So far, results seem promising.
Dr. David Cleveland, pediatric heart surgeon at Children’s Hospital and UAB, says it can be a challenge when a baby needs a heart transplant.
“So the number of donors is just not there,” Cleveland says. “I mean, we’ve had babies sit there and wait for nine months in our unit, and then we’ve had a number of babies that die, waiting for hearts. And so there’s a tremendous need.”
To meet that need, one idea is that a baby could use a pig heart to stay alive until a human heart becomes available. Before that can happen, scientists have to make sure the human body will accept the animal organ. Over the years, they have figured out how to genetically modify pigs to minimize the odds of rejection. In their recent study, Cleveland and fellow UAB researchers checked to see how infant’s blood reacted to the blood of these altered pigs.
“I was incredibly surprised that there’s really not a lot of antibodies to these genetically-modified pigs,” Cleveland says. “Which tells you that they (infants) aren’t going to immediately reject it.”
It is progress, but Cleveland says we are still a long way from transplanting pig hearts into people. More thorough testing is needed and scientists need to see how it does on non-human primates before clinical trials can happen with humans.
Photo by Sasint
Editor Note: Children’s Hospital of Alabama is a sponsor of WBHM programming. WBHM’s news and business departments operate separately
Why is the U.S. attacking Iran? Six things to know
The U.S. and Israel launched military strikes in Iran, targeting Khamenei and the Iranian president. "Operation Epic Fury" will be "massive and ongoing," President Trump said Saturday morning.
Sen. Tim Kaine calls on the Senate to vote on the war powers resolution
NPR's Scott Simon talks to Sen. Tim Kaine, D-Va., about the U.S. strikes on Iran.
Political science expert weighs in on Iran’s nuclear program in light of U.S. strikes
NPR's Scott Simon speaks to Ariane Tabatabai, the Public Service Fellow at Lawfare, about U.S. attacks on Iran and how President Trump's calls for regime change might be received there.
Week in Politics: Does Trump have political support for his actions in Iran?
We look at what President Trump's decision to attack Iran means, what kind of support he has in Iran and what this moment means for his administration.
Unlocking the secrets of an ancient plague
The first historically recorded pandemic is believed to have struck the walled city of Jirash, in what is now modern-day Jordan, in the 7th century. A new study reveals details about those who died.
Panic, fury, and some hope, in Iran as U.S. launches strikes
In Tehran, panicked residents rushed home to shelter and terrified children poured out of classrooms as U.S. air strikes hit the capitol.
