Pig Hearts Could Keep Babies Awaiting Transplants Alive
Scientists hope in the future, pig hearts can be a temporary solution for babies who need a transplant. UAB researchers recently presented a study about this at The Society of Thoracic Surgeons’ annual meeting. The goal is to prevent pig hearts from being rejected. So far, results seem promising.
Dr. David Cleveland, pediatric heart surgeon at Children’s Hospital and UAB, says it can be a challenge when a baby needs a heart transplant.
“So the number of donors is just not there,” Cleveland says. “I mean, we’ve had babies sit there and wait for nine months in our unit, and then we’ve had a number of babies that die, waiting for hearts. And so there’s a tremendous need.”
To meet that need, one idea is that a baby could use a pig heart to stay alive until a human heart becomes available. Before that can happen, scientists have to make sure the human body will accept the animal organ. Over the years, they have figured out how to genetically modify pigs to minimize the odds of rejection. In their recent study, Cleveland and fellow UAB researchers checked to see how infant’s blood reacted to the blood of these altered pigs.
“I was incredibly surprised that there’s really not a lot of antibodies to these genetically-modified pigs,” Cleveland says. “Which tells you that they (infants) aren’t going to immediately reject it.”
It is progress, but Cleveland says we are still a long way from transplanting pig hearts into people. More thorough testing is needed and scientists need to see how it does on non-human primates before clinical trials can happen with humans.
Photo by Sasint
Editor Note: Children’s Hospital of Alabama is a sponsor of WBHM programming. WBHM’s news and business departments operate separately
How Alabama’s first commuted death sentence this century came about
Robin "Rocky" Myers has been on Alabama’s death row for more than 30 years. Then, on February 28, he became the first Alabamian this century to have his death sentence commuted.
Steve Reich has always been to able to hear the pulse
The 88-year-old composer, who talks as fast as the interlocking phrases of his music, looks back on crucial moments in a career that moved minimalism into the mainstream.
There’s a lot to unpack in ‘Black Bag’ — a witty, sexy spy thriller
Cate Blanchett and Michael Fassbender play a high-ranking spy couple in Steven Soderbergh's new film. Black Bag offers Bond-style globe-trotting intrigue and marital dramedy.
Photos: Across the U.S., sky gazers marvel at the blood moon lunar eclipse
As the moon moved through the shadow of the Earth, it was also being illuminated by light from the sun — causing the moon to appear as if dipped in a deep red hue in a stunning celestial sight.
Hamas says it’s willing to release the five American hostages in Gaza
Hamas, the militant group the U.S. has labeled as terrorists, says it's willing to release the one living American hostage and bodies of four others it's held in Gaza since the 2023 attacks in Israel.
Dorothy Thompson: The journalist who warned us about Hitler
Dorothy Thompson saw the rise of Nazi Germany as a foreign correspondent in Berlin. A new series from Radio Diaries tells the story of Thompson's career as a radio broadcaster.
